Joseph, Bertrand
Mitochondrial dysfunction is an essential step for killing of non-small cell lung carcinomas resistant to conventional treatment. [electronic resource]
- Oncogene Jan 2002
- 65-77 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
ISSN: 0950-9232
Standard No.: 10.1038/sj.onc.1205018 doi
Subjects--Topical Terms: Amino Acid Chloromethyl Ketones--pharmacology Apoptosis--drug effects Apoptosis Inducing Factor Carcinoma, Non-Small-Cell Lung--pathology Carcinoma, Small Cell--pathology Caspase 3 Caspase 7 Caspases--biosynthesis Cell Cycle--drug effects Cell Nucleus--drug effects Cysteine Proteinase Inhibitors--pharmacology Cytochrome c Group--analysis Drug Resistance, Neoplasm Enzyme Activation--drug effects Enzyme Inhibitors--pharmacology Enzyme Precursors--biosynthesis Flavoproteins--physiology Gamma Rays Humans Jurkat Cells--drug effects Lung Neoplasms--pathology Membrane Potentials--drug effects Membrane Proteins--physiology Mitochondria--physiology Poly(ADP-ribose) Polymerases--metabolism Protein Transport Radiation Tolerance Reactive Oxygen Species--metabolism Recombinant Fusion Proteins--physiology Staurosporine--pharmacology Superoxides--metabolism Tumor Cells, Cultured--drug effects