TY - GEN AU - Leavitt,S AU - Freire,E TI - Direct measurement of protein binding energetics by isothermal titration calorimetry SN - 0959-440X PY - 2002///0412 KW - Calorimetry KW - methods KW - Entropy KW - HIV Protease KW - chemistry KW - In Vitro Techniques KW - Protein Binding KW - Protons KW - Thermodynamics N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.; Review UR - https://doi.org/10.1016/s0959-440x(00)00248-7 ER -