TY  - GEN
AU  - Jeffy,Brandon D
AU  - Chirnomas,Ryan B
AU  - Chen,Eddy J
AU  - Gudas,Jean M
AU  - Romagnolo,Donato F
TI  - Activation of the aromatic hydrocarbon receptor pathway is not sufficient for transcriptional repression of BRCA-1: requirements for metabolism of benzo[a]pyrene to 7r,8t-dihydroxy-9t,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene
SN  - 0008-5472
PY  - 2002///0212
KW  - 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
KW  - metabolism
KW  - BRCA1 Protein
KW  - biosynthesis
KW  - Benzo(a)pyrene
KW  - Biotransformation
KW  - Breast Neoplasms
KW  - chemically induced
KW  - Carcinogens
KW  - Down-Regulation
KW  - Gene Expression Profiling
KW  - Gene Expression Regulation, Neoplastic
KW  - drug effects
KW  - Genes, BRCA1
KW  - Humans
KW  - Polychlorinated Dibenzodioxins
KW  - toxicity
KW  - Promoter Regions, Genetic
KW  - RNA, Messenger
KW  - Receptors, Aryl Hydrocarbon
KW  - Reverse Transcriptase Polymerase Chain Reaction
KW  - Signal Transduction
KW  - Transcription, Genetic
KW  - Tumor Cells, Cultured
KW  - Tumor Suppressor Protein p53
KW  - genetics
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S
ER  -