TY - GEN AU - Chen,Songhai AU - Lin,Fang AU - Xu,Ming AU - Graham,Robert M TI - Phe(303) in TMVI of the alpha(1B)-adrenergic receptor is a key residue coupling TM helical movements to G-protein activation SN - 0006-2960 PY - 2002///0204 KW - Amino Acid Sequence KW - Animals KW - Binding Sites KW - COS Cells KW - Cell Membrane KW - metabolism KW - Cricetinae KW - Cysteine KW - chemistry KW - Cytoplasm KW - Dose-Response Relationship, Drug KW - Epinephrine KW - GTP-Binding Proteins KW - Humans KW - Hydrogen-Ion Concentration KW - Hydrolysis KW - Ligands KW - Molecular Sequence Data KW - Mutagenesis, Site-Directed KW - Mutation KW - Phenylalanine KW - Phosphatidylinositols KW - Protein Binding KW - Receptors, Adrenergic, alpha-1 KW - Sequence Homology, Amino Acid KW - Signal Transduction KW - Temperature KW - Time Factors KW - Transfection N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1021/bi011868k ER -