Borthwick, Alan D <br/><br/>
Design and synthesis of pyrrolidine-5,5-trans-lactams (5-oxohexahydropyrrolo[3,2-b]pyrroles) as novel mechanism-based inhibitors of human cytomegalovirus protease. 2. Potency and chirality.  [electronic resource] 

 -  Journal of medicinal chemistry  Jan 2002 
 - 1-18 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm0102203  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antiviral Agents--chemical synthesis<br/>Binding Sites<br/>Crystallography, X-Ray<br/>Cytomegalovirus--chemistry<br/>Lactams--chemical synthesis<br/>Mass Spectrometry<br/>Models, Molecular<br/>Protease Inhibitors--chemical synthesis<br/>Pyrroles--chemical synthesis<br/>Serine Endopeptidases--chemistry<br/>Stereoisomerism<br/>Structure-Activity Relationship