TY - GEN AU - Yang,J AU - Niu,T AU - Zhang,A AU - Mishra,A K AU - Zhao,Z J AU - Zhou,G W TI - Relation between the flexibility of the WPD loop and the activity of the catalytic domain of protein tyrosine phosphatase SHP-1 SN - 0730-2312 PY - 2002///0313 KW - Alanine KW - Catalytic Domain KW - physiology KW - Conserved Sequence KW - genetics KW - Enzyme Activation KW - Intracellular Signaling Peptides and Proteins KW - Kinetics KW - Models, Molecular KW - Mutation KW - Pliability KW - Proline KW - Protein Conformation KW - Protein Structure, Secondary KW - Protein Tyrosine Phosphatase, Non-Receptor Type 11 KW - Protein Tyrosine Phosphatase, Non-Receptor Type 6 KW - Protein Tyrosine Phosphatases KW - chemistry KW - Sequence Homology, Amino Acid KW - Structure-Activity Relationship N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1002/jcb.1265 ER -