TY - GEN AU - Ruiz de Azúa,I AU - Lumbreras,M A AU - Zalduegui,A AU - Baamonde,C AU - Dierssen,M AU - Flórez,J AU - Sallés,J TI - Reduced phospholipase C-beta activity and isoform expression in the cerebellum of TS65Dn mouse: a model of Down syndrome SN - 0360-4012 PY - 2002///0124 KW - Animals KW - Calcium KW - metabolism KW - Cell Membrane KW - drug effects KW - Cerebellum KW - Cerebral Cortex KW - enzymology KW - Disease Models, Animal KW - Dose-Response Relationship, Drug KW - Down Syndrome KW - Down-Regulation KW - GTP-Binding Proteins KW - Gene Expression Regulation, Enzymologic KW - Guanosine 5'-O-(3-Thiotriphosphate) KW - pharmacokinetics KW - Isoenzymes KW - deficiency KW - Male KW - Mice KW - Mice, Neurologic Mutants KW - Muscarinic Agonists KW - pharmacology KW - Muscarinic Antagonists KW - Phosphatidylinositol 4,5-Diphosphate KW - genetics KW - Phospholipase C beta KW - Protein Isoforms KW - Receptor, Serotonin, 5-HT2A KW - Receptors, Muscarinic KW - Receptors, Serotonin KW - Serotonin Antagonists KW - Serotonin Receptor Agonists KW - Signal Transduction KW - Subcellular Fractions KW - Tritium KW - Type C Phospholipases N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1002/jnr.10019 ER -