Ficker, Eckhard <br/><br/>
The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations.  [electronic resource] 

 -  The Journal of biological chemistry  Feb 2002 
 - 4989-98 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0021-9258 
<br/><br/><label>Standard No.: </label>10.1074/jbc.M107345200  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Anti-Arrhythmia Agents--pharmacology<br/>Astemizole--pharmacology<br/>Benzimidazoles--pharmacology<br/>Binding Sites<br/>Blotting, Western<br/>Cation Transport Proteins<br/>Cell Line<br/>Cell Membrane--metabolism<br/>Cisapride--pharmacology<br/>DNA-Binding Proteins<br/>Dose-Response Relationship, Drug<br/>ERG1 Potassium Channel<br/>Electrophysiology<br/>Ether-A-Go-Go Potassium Channels<br/>Gastrointestinal Agents--pharmacology<br/>Histamine H1 Antagonists--pharmacology<br/>Humans<br/>Inhibitory Concentration 50<br/>Ions<br/>Long QT Syndrome--genetics<br/>Models, Chemical<br/>Mutagenesis, Site-Directed<br/>Mutation<br/>Patch-Clamp Techniques<br/>Piperidines--pharmacology<br/>Potassium Channels--chemistry<br/>Potassium Channels, Voltage-Gated<br/>Protein Folding<br/>Pyridines--pharmacology<br/>Quaternary Ammonium Compounds--chemistry<br/>Quinidine--pharmacology<br/>Structure-Activity Relationship<br/>Trans-Activators<br/>Transcriptional Regulator ERG