Nerve growth factor in combination with second messenger analogues causes neuronal differentiation of PC12 cells expressing a dominant inhibitory Ras protein without inducing activation of extracellular signal-regulated kinases. [electronic resource]
- The European journal of neuroscience Nov 2001
- 1445-54 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0953-816X
10.1046/j.0953-816x.2001.01787.x doi
Active Transport, Cell Nucleus--drug effects Animals Bucladesine--pharmacology Cell Differentiation--drug effects Enzyme Inhibitors--pharmacology Immunohistochemistry Ionomycin--pharmacology Mitogen-Activated Protein Kinases--drug effects Nerve Growth Factor--metabolism Nervous System--embryology Neurites--drug effects PC12 Cells--cytology Phosphorylation--drug effects Protein Transport--drug effects Rats Second Messenger Systems--drug effects Signal Transduction--drug effects ras Proteins--drug effects