Loss of DNA mismatch repair imparts defective cdc2 signaling and G(2) arrest responses without altering survival after ionizing radiation. [electronic resource]
- Cancer research Nov 2001
- 8290-7 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0008-5472
Adaptor Proteins, Signal Transducing Base Pair Mismatch CDC2 Protein Kinase--metabolism Carrier Proteins Cell Survival--drug effects Colorectal Neoplasms--metabolism DNA Repair--physiology Endometrial Neoplasms--metabolism Female G2 Phase--drug effects Humans MutL Protein Homolog 1 Neoplasm Proteins--deficiency Nuclear Proteins Ovarian Neoplasms--metabolism Phosphorylation S Phase--drug effects Signal Transduction--physiology Thioguanine--pharmacology Tumor Cells, Cultured