TY - GEN AU - Hesse,M AU - Modolell,M AU - La Flamme,A C AU - Schito,M AU - Fuentes,J M AU - Cheever,A W AU - Pearce,E J AU - Wynn,T A TI - Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of L-arginine metabolism SN - 0022-1767 PY - 2002///0102 KW - Animals KW - Arginase KW - antagonists & inhibitors KW - Arginine KW - metabolism KW - Cells, Cultured KW - Disease Models, Animal KW - Eflornithine KW - pharmacology KW - Enzyme Activation KW - drug effects KW - Enzyme Induction KW - Enzyme Inhibitors KW - Female KW - Granuloma KW - enzymology KW - Interleukin-12 KW - physiology KW - Liver KW - Liver Cirrhosis KW - Lung Diseases, Parasitic KW - Macrophage Activation KW - Macrophages KW - immunology KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Mycobacterium avium KW - Nitric Oxide Synthase KW - biosynthesis KW - Nitric Oxide Synthase Type II KW - Ornithine Decarboxylase Inhibitors KW - Ovum KW - Proline KW - Schistosomiasis mansoni KW - Th1 Cells KW - Th2 Cells KW - Tuberculosis KW - Up-Regulation KW - genetics N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.4049/jimmunol.167.11.6533 ER -