Altering the GTP binding site of the DNA/RNA-binding protein, Translin/TB-RBP, decreases RNA binding and may create a dominant negative phenotype. [electronic resource]
- Nucleic acids research Nov 2001
- 4433-40 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
1362-4962
10.1093/nar/29.21.4433 doi
3T3 Cells Allosteric Regulation Allosteric Site Amino Acid Sequence Animals Carrier Proteins--metabolism Cell Death DNA--genetics DNA-Binding Proteins--chemistry Dimerization Genes, Dominant--genetics Guanosine 5'-O-(3-Thiotriphosphate)--metabolism Guanosine Diphosphate--metabolism Guanosine Triphosphate--metabolism Humans Male Mice Mutation--genetics Nuclear Proteins--metabolism Phenotype Protein Binding Protein Structure, Tertiary RNA--genetics RNA-Binding Proteins--chemistry Testis--metabolism Two-Hybrid System Techniques