Leithäuser, F

Isotype-switched immunoglobulin genes with a high load of somatic hypermutation and lack of ongoing mutational activity are prevalent in mediastinal B-cell lymphoma. [electronic resource] - Blood Nov 2001 - 2762-70 p. digital

Publication Type: Journal Article

0006-4971

10.1182/blood.v98.9.2762 doi


Adult
Antibodies, Neoplasm--analysis
Base Sequence
Clone Cells--immunology
Female
Gene Expression Regulation
Gene Rearrangement
Humans
Immunoglobulin Class Switching--genetics
Immunoglobulin G--drug effects
Immunoglobulin Heavy Chains--genetics
Immunoglobulin Variable Region--genetics
Lymphoma, B-Cell--genetics
Lymphoma, Large B-Cell, Diffuse--genetics
Male
Mediastinal Neoplasms--genetics
Middle Aged
Molecular Sequence Data
Mutation
RNA, Messenger--analysis
RNA, Neoplasm--analysis
Somatic Hypermutation, Immunoglobulin--genetics
Tumor Cells, Cultured