TY - GEN AU - McKenna,I M AU - Ramakrishna,G AU - Diwan,B A AU - Kang,Y AU - Shiao,Y H AU - Wakefield,L M AU - Powell,D A AU - Anderson,L M AU - Jakowlew,S B TI - Heterozygous inactivation of TGF-beta1 increases the susceptibility to chemically induced mouse lung tumorigenesis independently of mutational activation of K-ras SN - 0378-4274 PY - 2002///0116 KW - Adenoma KW - chemically induced KW - Animals KW - Carcinogenicity Tests KW - Carcinogens KW - administration & dosage KW - Carcinoma KW - Crosses, Genetic KW - DNA Mutational Analysis KW - DNA, Neoplasm KW - chemistry KW - Female KW - Genes, ras KW - drug effects KW - Genetic Predisposition to Disease KW - Genotype KW - Heterozygote KW - Lung Neoplasms KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Mice, Inbred Strains KW - Mutagenicity Tests KW - Mutation KW - Polymerase Chain Reaction KW - Polymorphism, Single-Stranded Conformational KW - Transforming Growth Factor beta KW - deficiency KW - Transforming Growth Factor beta1 KW - Urethane N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/s0378-4274(01)00393-9 ER -