Hakimelahi, G H

Design, synthesis, and biological evaluation of novel nucleoside and nucleotide analogues as agents against DNA viruses and/or retroviruses. [electronic resource] - Journal of medicinal chemistry Oct 2001 - 3710-20 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-2623

10.1021/jm010216r doi


Adenine--analogs & derivatives
Adenine Nucleotides--chemical synthesis
Adenosine Deaminase Inhibitors
Animals
Antineoplastic Agents--chemical synthesis
Antiviral Agents--chemical synthesis
Cell Line
Chlorocebus aethiops
DNA Viruses--drug effects
Drug Design
Enzyme Inhibitors--chemical synthesis
Lethal Dose 50
Leukemia, Experimental--drug therapy
Mice
Nucleosides--chemical synthesis
Nucleotides--chemical synthesis
Phosphoric Diester Hydrolases--chemistry
Phosphorylation
Retroviridae--drug effects
Retroviridae Infections--drug therapy
Simplexvirus--enzymology
Snake Venoms--enzymology
Spleen--enzymology
Thymidine Kinase--antagonists & inhibitors
Tumor Virus Infections--drug therapy
Vero Cells