TY  - GEN
AU  - Lietha,D
AU  - Chirgadze,D Y
AU  - Mulloy,B
AU  - Blundell,T L
AU  - Gherardi,E
TI  - Crystal structures of NK1-heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor
SN  - 0261-4189
PY  - 2001///1205
KW  - Animals
KW  - Binding Sites
KW  - Cell Line
KW  - Crystallography, X-Ray
KW  - Dimerization
KW  - Dogs
KW  - Drug Design
KW  - Heparin
KW  - chemistry
KW  - Heparitin Sulfate
KW  - metabolism
KW  - Hepatocyte Growth Factor
KW  - Humans
KW  - Kidney
KW  - Kringles
KW  - Macromolecular Substances
KW  - Models, Molecular
KW  - Mutagenesis, Site-Directed
KW  - Peptide Fragments
KW  - Protein Binding
KW  - Protein Conformation
KW  - Protein Structure, Tertiary
KW  - Proto-Oncogene Proteins c-met
KW  - antagonists & inhibitors
KW  - RNA Splicing
KW  - Recombinant Fusion Proteins
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1093/emboj/20.20.5543
ER  -