Freson, K <br/><br/>
Genetic variation of the extra-large stimulatory G protein alpha-subunit leads to Gs hyperfunction in platelets and is a risk factor for bleeding.  [electronic resource] 

 -  Thrombosis and haemostasis  Sep 2001 
 - 733-8 p.  digital 
<br/><br/> Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0340-6245 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Abnormalities, Multiple--genetics<br/>Adenosine--pharmacology<br/>Adenylyl Cyclases--metabolism<br/>Adolescent<br/>Alprostadil--pharmacology<br/>Alternative Splicing<br/>Amino Acid Sequence<br/>Amino Acid Substitution<br/>Bleeding Time<br/>Blood Platelets--physiology<br/>Child<br/>Chromogranins<br/>Cyclic AMP--biosynthesis<br/>Female<br/>Fingers--abnormalities<br/>GTP-Binding Protein alpha Subunits, Gs--genetics<br/>Gene Frequency<br/>Genomic Imprinting<br/>Hemorrhagic Disorders--epidemiology<br/>Heterotrimeric GTP-Binding Proteins<br/>Humans<br/>Hyperkinesis--genetics<br/>Hypoparathyroidism--genetics<br/>Iloprost--pharmacology<br/>Intellectual Disability--genetics<br/>Male<br/>Molecular Sequence Data<br/>Muscle Hypotonia--genetics<br/>Mutagenesis, Insertional<br/>Nerve Tissue Proteins<br/>Phenotype<br/>Platelet Aggregation--drug effects<br/>Platelet Function Tests<br/>Polymorphism, Genetic<br/>Protein Subunits<br/>Repetitive Sequences, Amino Acid<br/>Risk Factors<br/>Second Messenger Systems<br/>Structure-Activity Relationship<br/>Wounds and Injuries--complications