Butler, J E

Antibody repertoire development in fetal and neonatal piglets. IV. Switch recombination, primarily in fetal thymus, occurs independent of environmental antigen and is only weakly associated with repertoire diversification. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Sep 2001 - 3239-49 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

0022-1767

10.4049/jimmunol.167.6.3239 doi


Animals
Antibody Diversity
Antigens--immunology
Antigens, Viral--immunology
Colostrum--immunology
DNA Nucleotidyltransferases--metabolism
Environment
Female
Fetal Blood--immunology
Fetal Diseases--embryology
Germ-Free Life
Gestational Age
Immunoglobulin A--biosynthesis
Immunoglobulin Class Switching
Immunoglobulin G--biosynthesis
Immunoglobulin Isotypes--blood
Immunoglobulin M--biosynthesis
Immunoglobulin Switch Region
Male
Maternal-Fetal Exchange
Parotid Gland--immunology
Porcine Reproductive and Respiratory Syndrome--embryology
Pregnancy
Recombination, Genetic
Swine--embryology
Swine Diseases--embryology
Thymus Gland--embryology
Transcription, Genetic
VDJ Recombinases