Antibody repertoire development in fetal and neonatal piglets. IV. Switch recombination, primarily in fetal thymus, occurs independent of environmental antigen and is only weakly associated with repertoire diversification. [electronic resource]
- Journal of immunology (Baltimore, Md. : 1950) Sep 2001
- 3239-49 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
0022-1767
10.4049/jimmunol.167.6.3239 doi
Animals Antibody Diversity Antigens--immunology Antigens, Viral--immunology Colostrum--immunology DNA Nucleotidyltransferases--metabolism Environment Female Fetal Blood--immunology Fetal Diseases--embryology Germ-Free Life Gestational Age Immunoglobulin A--biosynthesis Immunoglobulin Class Switching Immunoglobulin G--biosynthesis Immunoglobulin Isotypes--blood Immunoglobulin M--biosynthesis Immunoglobulin Switch Region Male Maternal-Fetal Exchange Parotid Gland--immunology Porcine Reproductive and Respiratory Syndrome--embryology Pregnancy Recombination, Genetic Swine--embryology Swine Diseases--embryology Thymus Gland--embryology Transcription, Genetic VDJ Recombinases