Hanna, Z <br/><br/>
The pathogenicity of human immunodeficiency virus (HIV) type 1 Nef in CD4C/HIV transgenic mice is abolished by mutation of its SH3-binding domain, and disease development is delayed in the absence of Hck.  [electronic resource] 

 -  Journal of virology  Oct 2001 
 - 9378-92 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0022-538X 
<br/><br/><label>Standard No.: </label>10.1128/JVI.75.19.9378-9392.2001  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>CD4 Antigens--genetics<br/>Genes, nef<br/>HIV Infections--genetics<br/>HIV-1--genetics<br/>Humans<br/>Mice<br/>Mice, Transgenic<br/>Mutation<br/>Protein-Tyrosine Kinases--genetics<br/>Proto-Oncogene Proteins--genetics<br/>Proto-Oncogene Proteins c-hck<br/>Virulence--genetics<br/>Virus Replication--genetics<br/>src Homology Domains