TY - GEN AU - Caliendo,G AU - Santagada,V AU - Perissutti,E AU - Severino,B AU - Fiorino,F AU - Warner,T D AU - Wallace,J L AU - Ifa,D R AU - Antunes,E AU - Cirino,G AU - de Nucci,G TI - Synthesis of substituted benzamides as anti-inflammatory agents that inhibit preferentially cyclooxygenase 1 but do not cause gastric damage SN - 0223-5234 PY - 2001///1205 KW - Animals KW - Anti-Inflammatory Agents KW - adverse effects KW - Benzamides KW - Cyclooxygenase 1 KW - Cyclooxygenase 2 KW - Cyclooxygenase 2 Inhibitors KW - Cyclooxygenase Inhibitors KW - Drug Design KW - Drug Evaluation, Preclinical KW - Edema KW - chemically induced KW - Food Deprivation KW - Inhibitory Concentration 50 KW - Isoenzymes KW - antagonists & inhibitors KW - Magnetic Resonance Spectroscopy KW - Male KW - Membrane Proteins KW - Prostaglandin-Endoperoxide Synthases KW - metabolism KW - Rats KW - Rats, Wistar KW - Sheep KW - Stomach KW - drug effects KW - Structure-Activity Relationship KW - Substrate Specificity N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/s0223-5234(01)01251-x ER -