Caliendo, G <br/><br/>
Synthesis of substituted benzamides as anti-inflammatory agents that inhibit preferentially cyclooxygenase 1 but do not cause gastric damage.  [electronic resource] 

 -  European journal of medicinal chemistry  Jun 2001 
 - 517-30 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0223-5234 
<br/><br/><label>Standard No.: </label>10.1016/s0223-5234(01)01251-x  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Anti-Inflammatory Agents--adverse effects<br/>Benzamides--adverse effects<br/>Cyclooxygenase 1<br/>Cyclooxygenase 2<br/>Cyclooxygenase 2 Inhibitors<br/>Cyclooxygenase Inhibitors--adverse effects<br/>Drug Design<br/>Drug Evaluation, Preclinical<br/>Edema--chemically induced<br/>Food Deprivation<br/>Inhibitory Concentration 50<br/>Isoenzymes--antagonists & inhibitors<br/>Magnetic Resonance Spectroscopy<br/>Male<br/>Membrane Proteins<br/>Prostaglandin-Endoperoxide Synthases--metabolism<br/>Rats<br/>Rats, Wistar<br/>Sheep<br/>Stomach--drug effects<br/>Structure-Activity Relationship<br/>Substrate Specificity