Glucose-dependent insulinotropic polypeptide is a growth factor for beta (INS-1) cells by pleiotropic signaling. [electronic resource]
- Molecular endocrinology (Baltimore, Md.) Sep 2001
- 1559-70 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0888-8809
10.1210/mend.15.9.0688 doi
Animals Cell Division Cell Line Cyclic AMP Response Element-Binding Protein--metabolism Cyclic AMP-Dependent Protein Kinase Type II Cyclic AMP-Dependent Protein Kinases--metabolism Dose-Response Relationship, Drug Enzyme Activation Gastric Inhibitory Polypeptide--pharmacology Glucose--pharmacology Growth Substances--metabolism Immunoblotting Islets of Langerhans--cytology Mitogen-Activated Protein Kinases--metabolism Models, Biological Phosphatidylinositol 3-Kinases--metabolism Phosphorylation Precipitin Tests Protein Isoforms--metabolism Protein Serine-Threonine Kinases Proto-Oncogene Proteins--metabolism Proto-Oncogene Proteins c-akt Rats Signal Transduction--physiology