TY  - GEN
AU  - Monteleone,G
AU  - Kumberova,A
AU  - Croft,N M
AU  - McKenzie,C
AU  - Steer,H W
AU  - MacDonald,T T
TI  - Blocking Smad7 restores TGF-beta1 signaling in chronic inflammatory bowel disease
SN  - 0021-9738
PY  - 2001///0920
KW  - Activin Receptors, Type I
KW  - Adolescent
KW  - Adult
KW  - Cells, Cultured
KW  - drug effects
KW  - Child
KW  - Colitis, Ulcerative
KW  - metabolism
KW  - Crohn Disease
KW  - Cytokines
KW  - biosynthesis
KW  - DNA-Binding Proteins
KW  - antagonists & inhibitors
KW  - Female
KW  - Gene Expression Regulation
KW  - Humans
KW  - Inflammatory Bowel Diseases
KW  - Interferon-gamma
KW  - Intestinal Mucosa
KW  - Male
KW  - Middle Aged
KW  - Oligodeoxyribonucleotides, Antisense
KW  - pharmacology
KW  - Organ Culture Techniques
KW  - Phosphorylation
KW  - Protein Processing, Post-Translational
KW  - Protein Serine-Threonine Kinases
KW  - Receptor, Transforming Growth Factor-beta Type I
KW  - Receptors, Transforming Growth Factor beta
KW  - Signal Transduction
KW  - Smad3 Protein
KW  - Smad7 Protein
KW  - Trans-Activators
KW  - Transforming Growth Factor beta
KW  - physiology
KW  - Transforming Growth Factor beta1
KW  - Tumor Necrosis Factor-alpha
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1172/JCI12821
ER  -