Monteleone, G <br/><br/>
Blocking Smad7 restores TGF-beta1 signaling in chronic inflammatory bowel disease.  [electronic resource] 

 -  The Journal of clinical investigation  Aug 2001 
 - 601-9 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0021-9738 
<br/><br/><label>Standard No.: </label>10.1172/JCI12821  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Activin Receptors, Type I<br/>Adolescent<br/>Adult<br/>Cells, Cultured--drug effects<br/>Child<br/>Colitis, Ulcerative--metabolism<br/>Crohn Disease--metabolism<br/>Cytokines--biosynthesis<br/>DNA-Binding Proteins--antagonists & inhibitors<br/>Female<br/>Gene Expression Regulation--drug effects<br/>Humans<br/>Inflammatory Bowel Diseases--metabolism<br/>Interferon-gamma--biosynthesis<br/>Intestinal Mucosa--drug effects<br/>Male<br/>Middle Aged<br/>Oligodeoxyribonucleotides, Antisense--pharmacology<br/>Organ Culture Techniques<br/>Phosphorylation<br/>Protein Processing, Post-Translational<br/>Protein Serine-Threonine Kinases--drug effects<br/>Receptor, Transforming Growth Factor-beta Type I<br/>Receptors, Transforming Growth Factor beta--drug effects<br/>Signal Transduction--drug effects<br/>Smad3 Protein<br/>Smad7 Protein<br/>Trans-Activators--antagonists & inhibitors<br/>Transforming Growth Factor beta--physiology<br/>Transforming Growth Factor beta1<br/>Tumor Necrosis Factor-alpha--biosynthesis