TY - GEN AU - Marx,S O AU - Marks,A R TI - Bench to bedside: the development of rapamycin and its application to stent restenosis SN - 1524-4539 PY - 2001///0913 KW - Angioplasty, Balloon, Coronary KW - adverse effects KW - Animals KW - Calcineurin Inhibitors KW - Carrier Proteins KW - metabolism KW - Cell Cycle Proteins KW - Cell Division KW - drug effects KW - Cell Movement KW - Clinical Trials as Topic KW - Clopidogrel KW - Coronary Artery Disease KW - surgery KW - Cyclin-Dependent Kinase Inhibitor p27 KW - Down-Regulation KW - Graft Occlusion, Vascular KW - diagnosis KW - Humans KW - Hyperplasia KW - Macromolecular Substances KW - Phosphotransferases (Alcohol Group Acceptor) KW - Platelet Aggregation Inhibitors KW - therapeutic use KW - Signal Transduction KW - Sirolimus KW - Stents KW - TOR Serine-Threonine Kinases KW - Tacrolimus KW - pharmacology KW - Tacrolimus Binding Protein 1A KW - Ticlopidine KW - analogs & derivatives KW - Tumor Suppressor Proteins KW - Tunica Media KW - Vascular Patency N1 - Publication Type: Editorial UR - https://doi.org/10.1161/01.cir.104.8.852 ER -