Beierschmitt, W P

Induction of hepatic microsomal drug-metabolizing enzymes by inhibitors of 5-lipoxygenase (5-LO): studies in rats and 5-LO knockout mice. [electronic resource] - Toxicological sciences : an official journal of the Society of Toxicology Sep 2001 - 15-21 p. digital

Publication Type: Journal Article

1096-6080

10.1093/toxsci/63.1.15 doi


Animals
Arachidonate 5-Lipoxygenase--deficiency
Cytochrome P-450 Enzyme System--biosynthesis
Dose-Response Relationship, Drug
Enzyme Induction
Hydroxyurea--analogs & derivatives
Lipoxygenase Inhibitors--pharmacology
Liver--drug effects
Male
Mice
Mice, Inbred DBA
Mice, Knockout
Microsomes, Liver--drug effects
NADH Dehydrogenase--biosynthesis
Organ Size--drug effects
Pyrans--pharmacology
Quinolones--pharmacology
Rats
Rats, Sprague-Dawley