Majumdar, S
Methotrexate suppresses NF-kappaB activation through inhibition of IkappaBalpha phosphorylation and degradation. [electronic resource]
- Journal of immunology (Baltimore, Md. : 1950) Sep 2001
- 2911-20 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
ISSN: 0022-1767
Standard No.: 10.4049/jimmunol.167.5.2911 doi
Subjects--Topical Terms: 5'-Nucleotidase--antagonists & inhibitors Adenosine--metabolism Adenosine Triphosphate--analogs & derivatives Base Sequence DNA-Binding Proteins--metabolism Enzyme Activation--drug effects Enzyme Inhibitors--pharmacology Folic Acid Antagonists--pharmacology Gene Expression--drug effects Genes, Reporter--drug effects HeLa Cells Humans I-kappa B Kinase I-kappa B Proteins Jurkat Cells Leucovorin--pharmacology Methotrexate--pharmacology NF-KappaB Inhibitor alpha NF-kappa B--metabolism Oligodeoxyribonucleotides--genetics Phosphorylation Protein Serine-Threonine Kinases--metabolism Purinergic P1 Receptor Antagonists Receptor, Adenosine A2B Theobromine--analogs & derivatives Thymidine--pharmacology Transcription Factor AP-1--metabolism Tumor Necrosis Factor-alpha--pharmacology U937 Cells