Hu, X <br/><br/>
An IkappaBalpha inhibitor causes leukemia cell death through a p38 MAP kinase-dependent, NF-kappaB-independent mechanism.  [electronic resource] 

 -  Cancer research  Aug 2001 
 - 6290-6 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0008-5472 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Activating Transcription Factor 2<br/>Anti-Infective Agents--antagonists & inhibitors<br/>Apoptosis--drug effects<br/>Cyclic AMP Response Element-Binding Protein--metabolism<br/>DNA-Binding Proteins--antagonists & inhibitors<br/>Dose-Response Relationship, Drug<br/>Enzyme Activation<br/>Enzyme Inhibitors--pharmacology<br/>Humans<br/>I-kappa B Proteins<br/>Imidazoles--pharmacology<br/>Leukemia, Myeloid--enzymology<br/>MAP Kinase Kinase Kinase 1<br/>Mitogen-Activated Protein Kinases--antagonists & inhibitors<br/>NF-KappaB Inhibitor alpha<br/>NF-kappa B--physiology<br/>Necrosis<br/>Nitriles<br/>Phosphorylation<br/>Protein Serine-Threonine Kinases--antagonists & inhibitors<br/>Pyridines--pharmacology<br/>Sulfones<br/>Transcription Factors--metabolism<br/>Tumor Cells, Cultured--drug effects<br/>U937 Cells<br/>p38 Mitogen-Activated Protein Kinases