In vivo transtracheal adenovirus-mediated transfer of human interleukin-10 gene to donor lungs ameliorates ischemia-reperfusion injury and improves early posttransplant graft function in the rat. [electronic resource]
- Human gene therapy Aug 2001
- 1513-26 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1043-0342
10.1089/10430340152480249 doi
Adenoviridae--genetics Animals Enzyme-Linked Immunosorbent Assay Gene Transfer Techniques Genetic Therapy--methods Immunohistochemistry Interferon-gamma--metabolism Interleukin-10--genetics Lung--metabolism Lung Transplantation--methods Male Oxygen--metabolism Peroxidase--metabolism Random Allocation Rats Rats, Inbred Lew Reperfusion Injury--therapy Time Factors Trachea--metabolism Transfection Tumor Necrosis Factor-alpha--metabolism