IL-6 deficiency allows for enhanced therapeutic value after bone marrow transplantation across a minor histocompatibility barrier in the twitcher (globoid cell leukodystrophy) mouse. [electronic resource]
- Journal of neuroscience research Aug 2001
- 298-307 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0360-4012
10.1002/jnr.1154 doi
Animals Astrocytes--pathology Blood-Brain Barrier Body Weight Bone Marrow Transplantation--immunology Brain--blood supply Demyelinating Diseases--immunology Female Gliosis--pathology Graft vs Host Disease--genetics Immunohistochemistry Interleukin-6--genetics Lectins Leukodystrophy, Globoid Cell--immunology Macrophages--pathology Male Mice Mice, Inbred C57BL Mice, Knockout Mice, Neurologic Mutants Minor Histocompatibility Antigens--immunology Myelin Basic Protein--analysis Serum Albumin--analysis Survival Rate beta-Galactosidase--genetics