Phosphoinositide 3-kinase-dependent membrane recruitment of p62(dok) is essential for its negative effect on mitogen-activated protein (MAP) kinase activation. [electronic resource]
- The Journal of experimental medicine Aug 2001
- 265-74 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0022-1007
10.1084/jem.194.3.265 doi
Adaptor Proteins, Signal Transducing Animals Binding Sites Biological Transport, Active--drug effects Cell Division Cell Line Cell Membrane--metabolism DNA-Binding Proteins Enzyme Activation Humans In Vitro Techniques Mice Mice, Knockout Mitogen-Activated Protein Kinases--metabolism Oncogene Proteins--metabolism Phosphatidylinositol 3-Kinases--metabolism Phosphatidylinositols--metabolism Phosphoproteins--chemistry Platelet-Derived Growth Factor--metabolism Protein Structure, Tertiary RNA-Binding Proteins Rats Receptors, Platelet-Derived Growth Factor--metabolism Signal Transduction ras GTPase-Activating Proteins--metabolism ras Proteins--metabolism