Ponec, D <br/><br/>
Recombinant tissue plasminogen activator (alteplase) for restoration of flow in occluded central venous access devices: a double-blind placebo-controlled trial--the Cardiovascular Thrombolytic to Open Occluded Lines (COOL) efficacy trial.  [electronic resource] 

 -  Journal of vascular and interventional radiology : JVIR  Aug 2001 
 - 951-5 p.  digital 
<br/><br/> Publication Type: Clinical Trial; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1051-0443 
<br/><br/><label>Standard No.: </label>10.1016/s1051-0443(07)61575-9  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Catheterization, Central Venous<br/>Catheters, Indwelling<br/>Double-Blind Method<br/>Equipment Failure<br/>Female<br/>Fibrinolytic Agents--administration & dosage<br/>Humans<br/>Male<br/>Middle Aged<br/>Placebos<br/>Thrombosis--drug therapy<br/>Tissue Plasminogen Activator--administration & dosage<br/>Treatment Outcome