Yaksh, T L <br/><br/>
The acute antihyperalgesic action of nonsteroidal, anti-inflammatory drugs and release of spinal prostaglandin E2 is mediated by the inhibition of constitutive spinal cyclooxygenase-2 (COX-2) but not COX-1.  [electronic resource] 

 -  The Journal of neuroscience : the official journal of the Society for Neuroscience  Aug 2001 
 - 5847-53 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>1529-2401 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Administration, Oral<br/>Animals<br/>Anti-Inflammatory Agents, Non-Steroidal--pharmacology<br/>Carrageenan<br/>Cyclooxygenase 1<br/>Cyclooxygenase 2<br/>Cyclooxygenase 2 Inhibitors<br/>Cyclooxygenase Inhibitors--administration & dosage<br/>Dinoprostone--biosynthesis<br/>Disease Models, Animal<br/>Dose-Response Relationship, Drug<br/>Hyperalgesia--chemically induced<br/>Ibuprofen--administration & dosage<br/>Injections, Intraperitoneal<br/>Injections, Spinal<br/>Isoenzymes--antagonists & inhibitors<br/>Male<br/>Membrane Proteins<br/>N-Methylaspartate<br/>Pain Measurement--drug effects<br/>Prostaglandin-Endoperoxide Synthases--metabolism<br/>Pyrazoles--administration & dosage<br/>Rats<br/>Rats, Sprague-Dawley<br/>Spinal Cord--drug effects<br/>Substance P