TY - GEN AU - Sambhara,S AU - Kurichh,A AU - Miranda,R AU - James,O AU - Underdown,B AU - Klein,M AU - Tartaglia,J AU - Burt,D TI - Severe impairment of primary but not memory responses to influenza viral antigens in aged mice: costimulation in vivo partially reverses impaired primary immune responses SN - 0008-8749 PY - 2001///0906 KW - Adjuvants, Immunologic KW - biosynthesis KW - Aging KW - immunology KW - Animals KW - Antibodies, Viral KW - Antigens, CD KW - Antigens, Viral KW - B7-1 Antigen KW - B7-2 Antigen KW - Cells, Cultured KW - Female KW - Genetic Vectors KW - Immunologic Memory KW - Influenza A virus KW - Influenza Vaccines KW - pharmacology KW - Lymphocyte Activation KW - Membrane Glycoproteins KW - Mice KW - Mice, Inbred DBA KW - Orthomyxoviridae Infections KW - Survival Analysis KW - T-Lymphocytes, Cytotoxic KW - Up-Regulation KW - Vaccinia virus KW - genetics N1 - Publication Type: Journal Article UR - https://doi.org/10.1006/cimm.2001.1799 ER -