Effect of CEP-751 (KT-6587) on neuroblastoma xenografts expressing TrkB. [electronic resource]
- Medical and pediatric oncology Jan 2001
- 181-4 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0098-1532
10.1002/1096-911X(20010101)36:1<181::AID-MPO1043>3.0.CO;2-Q doi
Animals Antineoplastic Agents--therapeutic use Apoptosis--drug effects Brain-Derived Neurotrophic Factor--pharmacology Carbazoles--therapeutic use Enzyme Activation--drug effects Enzyme Inhibitors--therapeutic use Female Humans In Situ Nick-End Labeling Mice Mice, Nude Neoplasm Proteins--antagonists & inhibitors Neuroblastoma--drug therapy Phosphorylation--drug effects Protein Processing, Post-Translational--drug effects Receptor, trkB--antagonists & inhibitors Reverse Transcriptase Polymerase Chain Reaction Transfection Tumor Cells, Cultured--metabolism Xenograft Model Antitumor Assays