TY  - GEN
AU  - Luzi,P
AU  - Rafi,M A
AU  - Zaka,M
AU  - Curtis,M
AU  - Vanier,M T
AU  - Wenger,D A
TI  - Generation of a mouse with low galactocerebrosidase activity by gene targeting: a new model of globoid cell leukodystrophy (Krabbe disease)
SN  - 1096-7192
PY  - 2001///1004
KW  - Age Factors
KW  - Alleles
KW  - Animals
KW  - Blotting, Northern
KW  - Body Weight
KW  - Brain
KW  - metabolism
KW  - COS Cells
KW  - Codon
KW  - DNA, Complementary
KW  - Disease Models, Animal
KW  - Electroporation
KW  - Galactosylceramidase
KW  - genetics
KW  - Gene Targeting
KW  - Genetic Vectors
KW  - Homozygote
KW  - Humans
KW  - Leukodystrophy, Globoid Cell
KW  - Mice
KW  - Mice, Transgenic
KW  - Microscopy, Electron
KW  - Models, Genetic
KW  - Mutation
KW  - Polymorphism, Genetic
KW  - Psychosine
KW  - biosynthesis
KW  - Recombinant Proteins
KW  - Recombination, Genetic
KW  - Reverse Transcriptase Polymerase Chain Reaction
KW  - Time Factors
KW  - Tissue Distribution
KW  - Transfection
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1006/mgme.2001.3194
ER  -