TY  - GEN
AU  - Beshore,D C
AU  - Bell,I M
AU  - Dinsmore,C J
AU  - Homnick,C F
AU  - Culberson,J C
AU  - Robinson,R G
AU  - Fernandes,C
AU  - Walsh,E S
AU  - Abrams,M T
AU  - Bhimnathwala,H G
AU  - Davide,J P
AU  - Ellis-Hutchings,M S
AU  - Huber,H A
AU  - Koblan,K S
AU  - Buser,C A
AU  - Kohl,N E
AU  - Lobell,R B
AU  - Chen,I W
AU  - McLoughlin,D A
AU  - Olah,T V
AU  - Graham,S L
AU  - Hartman,G D
AU  - Williams,T M
TI  - Evaluation of amino acid-based linkers in potent macrocyclic inhibitors of farnesyl-protein transferase
SN  - 0960-894X
PY  - 2001///0927
KW  - Alkyl and Aryl Transferases
KW  - antagonists & inhibitors
KW  - Amino Acids
KW  - chemistry
KW  - Animals
KW  - Cells, Cultured
KW  - Dogs
KW  - Enzyme Inhibitors
KW  - administration & dosage
KW  - Half-Life
KW  - Inhibitory Concentration 50
KW  - Metabolic Clearance Rate
KW  - physiology
KW  - Molecular Conformation
KW  - Protein Binding
KW  - drug effects
KW  - Rats
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/s0960-894x(01)00340-7
ER  -