Patel, R <br/><br/>
Simvastatin induces regression of cardiac hypertrophy and fibrosis and improves cardiac function in a transgenic rabbit model of human hypertrophic cardiomyopathy.  [electronic resource] 

 -  Circulation  Jul 2001 
 - 317-24 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>1524-4539 
<br/><br/><label>Standard No.: </label>10.1161/hc2801.094031  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Animals, Genetically Modified<br/>Cardiomegaly--complications<br/>Cardiomyopathy, Hypertrophic--complications<br/>Cell Line<br/>Disease Models, Animal<br/>Echocardiography<br/>Echocardiography, Doppler<br/>Endomyocardial Fibrosis--complications<br/>Hydroxymethylglutaryl-CoA Reductase Inhibitors--administration & dosage<br/>Hypolipidemic Agents--administration & dosage<br/>Mitogen-Activated Protein Kinase 1--metabolism<br/>Mitogen-Activated Protein Kinase 3<br/>Mitogen-Activated Protein Kinases--metabolism<br/>Mutation<br/>Myocardium--metabolism<br/>Myosin Heavy Chains--genetics<br/>Phenotype<br/>Rabbits<br/>Remission Induction<br/>Simvastatin--administration & dosage<br/>Ventricular Function, Left--drug effects<br/>ras Proteins--metabolism<br/>rhoA GTP-Binding Protein--metabolism