TY  - GEN
AU  - Meng,L
AU  - Ding,J
TI  - Induction of bulk and c-myc P2 promoter-specific DNA damage by an anti-topoisomerase II agent salvicine is an early event leading to apoptosis in HL-60 cells
SN  - 0014-5793
PY  - 2001///0809
KW  - Antineoplastic Agents, Phytogenic
KW  - pharmacology
KW  - Apoptosis
KW  - drug effects
KW  - Cell Division
KW  - DNA Damage
KW  - DNA Fragmentation
KW  - DNA Topoisomerases, Type II
KW  - metabolism
KW  - Dose-Response Relationship, Drug
KW  - Enzyme Inhibitors
KW  - Gene Expression Regulation
KW  - Genes, fos
KW  - genetics
KW  - Genes, jun
KW  - Genes, myc
KW  - HL-60 Cells
KW  - Humans
KW  - Naphthoquinones
KW  - chemistry
KW  - Promoter Regions, Genetic
KW  - RNA Stability
KW  - RNA, Messenger
KW  - Substrate Specificity
KW  - Topoisomerase II Inhibitors
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/s0014-5793(01)02633-3
ER  -