TY - GEN AU - Lu,X AU - Errington,J AU - Curtin,N J AU - Lunec,J AU - Newell,D R TI - The impact of p53 status on cellular sensitivity to antifolate drugs SN - 1078-0432 PY - 2001///1025 KW - Apoptosis KW - drug effects KW - Blotting, Western KW - Cell Cycle KW - Cell Division KW - Cyclin-Dependent Kinase Inhibitor p21 KW - Cyclins KW - genetics KW - DNA Mutational Analysis KW - DNA, Neoplasm KW - chemistry KW - Dose-Response Relationship, Drug KW - Folic Acid Antagonists KW - pharmacology KW - Gene Expression Regulation, Neoplastic KW - radiation effects KW - Genotype KW - Glutamates KW - Guanine KW - analogs & derivatives KW - Humans KW - Methotrexate KW - Mutation KW - Pemetrexed KW - Quinazolines KW - Sensitivity and Specificity KW - Tetrahydrofolates KW - Thiophenes KW - Tumor Cells, Cultured KW - Tumor Suppressor Protein p53 N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't ER -