Lu, X

The impact of p53 status on cellular sensitivity to antifolate drugs. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research Jul 2001 - 2114-23 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

1078-0432


Apoptosis--drug effects
Blotting, Western
Cell Cycle--drug effects
Cell Division--drug effects
Cyclin-Dependent Kinase Inhibitor p21
Cyclins--genetics
DNA Mutational Analysis
DNA, Neoplasm--chemistry
Dose-Response Relationship, Drug
Folic Acid Antagonists--pharmacology
Gene Expression Regulation, Neoplastic--radiation effects
Genotype
Glutamates--pharmacology
Guanine--analogs & derivatives
Humans
Methotrexate--pharmacology
Mutation
Pemetrexed
Quinazolines--pharmacology
Sensitivity and Specificity
Tetrahydrofolates--pharmacology
Thiophenes--pharmacology
Tumor Cells, Cultured
Tumor Suppressor Protein p53--genetics