TY  - GEN
AU  - Portrat,S
AU  - Mulatero,P
AU  - Curnow,K M
AU  - Chaussain,J L
AU  - Morel,Y
AU  - Pascoe,L
TI  - Deletion hybrid genes, due to unequal crossing over between CYP11B1 (11beta-hydroxylase) and CYP11B2(aldosterone synthase) cause steroid 11beta-hydroxylase deficiency and congenital adrenal hyperplasia
SN  - 0021-972X
PY  - 2001///0802
KW  - Adrenal Hyperplasia, Congenital
KW  - blood
KW  - Aldosterone
KW  - Androstenedione
KW  - Animals
KW  - Blotting, Southern
KW  - COS Cells
KW  - Child, Preschool
KW  - Cortodoxone
KW  - Crossing Over, Genetic
KW  - Cyproterone Acetate
KW  - therapeutic use
KW  - Cytochrome P-450 CYP11B2
KW  - genetics
KW  - DNA, Complementary
KW  - Exons
KW  - Gene Deletion
KW  - Gene Expression
KW  - Homozygote
KW  - Humans
KW  - Male
KW  - Polymerase Chain Reaction
KW  - Promoter Regions, Genetic
KW  - Puberty, Precocious
KW  - drug therapy
KW  - Renin
KW  - Steroid 11-beta-Hydroxylase
KW  - Transfection
N1  - Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1210/jcem.86.7.7671
ER  -