Portrat, S <br/><br/>
Deletion hybrid genes, due to unequal crossing over between CYP11B1 (11beta-hydroxylase) and CYP11B2(aldosterone synthase) cause steroid 11beta-hydroxylase deficiency and congenital adrenal hyperplasia.  [electronic resource] 

 -  The Journal of clinical endocrinology and metabolism  Jul 2001 
 - 3197-201 p.  digital 
<br/><br/> Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0021-972X 
<br/><br/><label>Standard No.: </label>10.1210/jcem.86.7.7671  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adrenal Hyperplasia, Congenital--blood<br/>Aldosterone--blood<br/>Androstenedione--blood<br/>Animals<br/>Blotting, Southern<br/>COS Cells<br/>Child, Preschool<br/>Cortodoxone--blood<br/>Crossing Over, Genetic<br/>Cyproterone Acetate--therapeutic use<br/>Cytochrome P-450 CYP11B2--genetics<br/>DNA, Complementary--genetics<br/>Exons<br/>Gene Deletion<br/>Gene Expression<br/>Homozygote<br/>Humans<br/>Male<br/>Polymerase Chain Reaction<br/>Promoter Regions, Genetic<br/>Puberty, Precocious--drug therapy<br/>Renin--blood<br/>Steroid 11-beta-Hydroxylase--genetics<br/>Transfection