TY - GEN AU - Tada,H AU - Maron,D J AU - Choi,E A AU - Barsoum,J AU - Lei,H AU - Xie,Q AU - Liu,W AU - Ellis,L AU - Moscioni,A D AU - Tazelaar,J AU - Fawell,S AU - Qin,X AU - Propert,K J AU - Davis,A AU - Fraker,D L AU - Wilson,J M AU - Spitz,F R TI - Systemic IFN-beta gene therapy results in long-term survival in mice with established colorectal liver metastases SN - 0021-9738 PY - 2001///0809 KW - Adenocarcinoma KW - drug therapy KW - Adenoviridae KW - genetics KW - Animals KW - Apoptosis KW - Colorectal Neoplasms KW - pathology KW - Cytomegalovirus KW - DNA, Complementary KW - administration & dosage KW - Female KW - Genes, Synthetic KW - Genetic Therapy KW - Genetic Vectors KW - Hepatocytes KW - metabolism KW - Humans KW - Injections, Intraperitoneal KW - Injections, Intravenous KW - Interferon-beta KW - Killer Cells, Natural KW - drug effects KW - Liver Neoplasms KW - Macrophages KW - Mice KW - Mice, Inbred BALB C KW - Mice, Nude KW - Mice, SCID KW - Neoplasm Transplantation KW - Neovascularization, Pathologic KW - Promoter Regions, Genetic KW - Recombinant Fusion Proteins KW - Tumor Cells, Cultured KW - transplantation KW - Xenograft Model Antitumor Assays N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1172/JCI9841 ER -