TY - GEN AU - Fitzjohn,S M AU - Morton,R A AU - Kuenzi,F AU - Rosahl,T W AU - Shearman,M AU - Lewis,H AU - Smith,D AU - Reynolds,D S AU - Davies,C H AU - Collingridge,G L AU - Seabrook,G R TI - Age-related impairment of synaptic transmission but normal long-term potentiation in transgenic mice that overexpress the human APP695SWE mutant form of amyloid precursor protein SN - 1529-2401 PY - 2001///0726 KW - Aging KW - genetics KW - Alzheimer Disease KW - Amyloid beta-Protein Precursor KW - biosynthesis KW - Animals KW - Disease Models, Animal KW - Electric Stimulation KW - Excitatory Amino Acid Antagonists KW - pharmacology KW - Excitatory Postsynaptic Potentials KW - drug effects KW - Genetic Predisposition to Disease KW - Hippocampus KW - Humans KW - In Vitro Techniques KW - Kynurenic Acid KW - Long-Term Potentiation KW - Mice KW - Mice, Transgenic KW - Mutation KW - Neuronal Plasticity KW - Plaque, Amyloid KW - pathology KW - Synaptic Transmission N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't ER -