TY - GEN AU - Ozawa,S AU - Shinohara,H AU - Kanayama ,H O AU - Bruns,C J AU - Bucana,C D AU - Ellis,L M AU - Davis,D W AU - Fidler,I J TI - Suppression of angiogenesis and therapy of human colon cancer liver metastasis by systemic administration of interferon-alpha SN - 1522-8002 PY - 2001///0927 KW - Animals KW - Apoptosis KW - Colonic Neoplasms KW - drug therapy KW - Dose-Response Relationship, Drug KW - Down-Regulation KW - Fibroblast Growth Factor 2 KW - biosynthesis KW - Humans KW - Immunohistochemistry KW - In Situ Hybridization KW - In Situ Nick-End Labeling KW - Interferon Type I KW - therapeutic use KW - Interferon alpha-2 KW - Interferon-alpha KW - Kinetics KW - Liver Neoplasms KW - blood supply KW - Male KW - Matrix Metalloproteinase 8 KW - Mice KW - Mice, Nude KW - Neoplasm Metastasis KW - Neovascularization, Pathologic KW - Platelet Endothelial Cell Adhesion Molecule-1 KW - Proliferating Cell Nuclear Antigen KW - RNA, Messenger KW - metabolism KW - Recombinant Proteins KW - Spleen KW - Time Factors KW - Tumor Cells, Cultured N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1038/sj.neo.7900128 ER -