Suppression of angiogenesis and therapy of human colon cancer liver metastasis by systemic administration of interferon-alpha. [electronic resource]
- Neoplasia (New York, N.Y.)
- 154-64 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
1522-8002
10.1038/sj.neo.7900128 doi
Animals Apoptosis Colonic Neoplasms--drug therapy Dose-Response Relationship, Drug Down-Regulation Fibroblast Growth Factor 2--biosynthesis Humans Immunohistochemistry In Situ Hybridization In Situ Nick-End Labeling Interferon Type I--therapeutic use Interferon alpha-2 Interferon-alpha--therapeutic use Kinetics Liver Neoplasms--blood supply Male Matrix Metalloproteinase 8--biosynthesis Mice Mice, Nude Neoplasm Metastasis Neovascularization, Pathologic Platelet Endothelial Cell Adhesion Molecule-1--biosynthesis Proliferating Cell Nuclear Antigen--biosynthesis RNA, Messenger--metabolism Recombinant Proteins Spleen--metabolism Time Factors Tumor Cells, Cultured