TY - GEN AU - Lauricella,M AU - Calvaruso,G AU - Carabillò,M AU - D'Anneo,A AU - Giuliano,M AU - Emanuele,S AU - Vento,R AU - Tesoriere,G TI - pRb suppresses camptothecin-induced apoptosis in human osteosarcoma Saos-2 cells by inhibiting c-Jun N-terminal kinase SN - 0014-5793 PY - 2001///0726 KW - Apoptosis KW - drug effects KW - Blotting, Western KW - Camptothecin KW - antagonists & inhibitors KW - Caspase 3 KW - Caspases KW - metabolism KW - Cell Cycle KW - Cell Size KW - Cell Survival KW - DNA Topoisomerases, Type I KW - Dose-Response Relationship, Drug KW - Enzyme Activation KW - Flow Cytometry KW - Glutathione KW - Humans KW - Hydrogen Peroxide KW - JNK Mitogen-Activated Protein Kinases KW - Mitogen-Activated Protein Kinases KW - Oxidative Stress KW - Phosphorylation KW - Poly(ADP-ribose) Polymerases KW - Proto-Oncogene Proteins c-jun KW - Retinoblastoma Protein KW - genetics KW - Time Factors KW - Topoisomerase I Inhibitors KW - Transfection KW - Tumor Cells, Cultured N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/s0014-5793(01)02553-4 ER -