Doğrul, Ahmet

L-type and T-type calcium channel blockade potentiate the analgesic effects of morphine and selective mu opioid agonist, but not to selective delta and kappa agonist at the level of the spinal cord in mice. [electronic resource] - Pain Jul 2001 - 61-68 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0304-3959

10.1016/S0304-3959(01)00293-7 doi


3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer--pharmacology
Amlodipine--pharmacology
Analgesics, Opioid--pharmacology
Animals
Calcium Channel Blockers--pharmacology
Calcium Channels, L-Type--drug effects
Calcium Channels, T-Type--drug effects
Drug Synergism
Enkephalin, Ala(2)-MePhe(4)-Gly(5)---pharmacology
Enkephalin, D-Penicillamine (2,5)---pharmacology
Male
Mibefradil--pharmacology
Mice
Morphine--pharmacology
Pain Measurement--drug effects
Postural Balance--drug effects
Receptors, Opioid, delta--agonists
Receptors, Opioid, kappa--agonists
Receptors, Opioid, mu--agonists
Spinal Cord--drug effects