Sp1 involvement in the 4beta-phorbol 12-myristate 13-acetate (TPA)-mediated increase in resistance to methotrexate in Chinese hamster ovary cells. [electronic resource]
- European journal of biochemistry Jun 2001
- 3163-73 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0014-2956
10.1046/j.1432-1327.2001.02198.x doi
Animals CHO Cells Cricetinae Drug Resistance Enzyme Activation--drug effects Methotrexate--pharmacology Plicamycin--pharmacology Promoter Regions, Genetic Protein Binding Protein Kinase C--metabolism Sp1 Transcription Factor--biosynthesis Tetradecanoylphorbol Acetate--pharmacology Tetrahydrofolate Dehydrogenase--biosynthesis Transfection Up-Regulation